[2016.10 \u2013 2018.06]<\/p>\n
I am involved in two other research projects in Prof. Bau\u2019s group at UPenn, both related to\u00a0HIV<\/strong>. The first project is about the\u00a0molecular testing\u00a0<\/strong>of\u00a0HIV detection. We focus on assays based on isothermal nucleic acid amplification which have a huge potential in cheap, on-site\u00a0point of care<\/strong> diagnosis. I myself contribute to modeling the amplification curve<\/strong>\u00a0to extract information including\u00a0sample numbers<\/strong>\u00a0and\u00a0amplification rates<\/strong>.<\/p>\n The second project focuses on the\u00a0tRNA retrograde transport<\/strong>, which is a critical process in\u00a0HIV infection<\/strong>. This phenomenon is responsible for the transport of the HIV reverse transcription complex into the nucleus, where it incorporates the viral genome into the host cell. This transport mechanism and condition is still unclear. We were able to do the experiments with fluorescent-labeled tRNA and monitored the real-time distribution of the tRNA. \u00a0I worked primarily for the\u00a0modeling<\/strong>\u00a0and\u00a0numerical simulation<\/strong>\u00a0of the process. We wish to find explanations for several features we observed from experiments by\u00a0adding different basic transport modules to the model.<\/p>\n","protected":false},"excerpt":{"rendered":" [2016.10 \u2013 2018.06] I am involved in two other research projects in Prof. Bau\u2019s group at UPenn, both related to\u00a0HIV. The first project is about the\u00a0molecular testing\u00a0of\u00a0HIV detection. We focus on assays based on isothermal nucleic acid amplification which have a huge potential in cheap, on-site\u00a0point of care diagnosis. I myself contribute to modeling the … <\/p>\n